Endocrine Abstracts

Survival rates following childhood cancer have improved, but the prevalence of late-effects and possible length of life remaining, mean that questions have been raised about the quality of life (QOL) of survivors. Results from a wide range of studies suggest that QOL among survivors is generally as good, or sometimes better than that reported by the normal population, or healthy siblings. However, considerable variation has been noted, depending on type of cancer and treatment...

Growth hormone treatment (GHT) is used to improve height, and potentially quality of life (QOL), in children with abnormal growth patterns. Previous QOL research suggests children with acquired growth hormone deficiency (AGHD) benefit more from GHT than those treated for other conditions.The aim was to determine child and parent reported QOL change over 1 year depending on GHT and diagnosis.One hundred and twenty-two children (mean...

Background: The National Institute for Clinical Excellence (NICE, 2002) suggests that measurement of quality of life (QOL) is necessary to assess the efficacy of GH treatment (GHT). A pilot study (Sheppard 2006) showed a greater improvement in QOL over the first 6 months of GHT for patients with acquired GH deficiency (AGHD) compared with idiopathic GH deficiency (IGHD).Method: In view of this, a longitudinal research study was set up to measure changes ...